FORMULATION DESIGN AND IN-VITRO EVALUATION OF ANTIPSYCHOTIC DRUG QUETIAPINE FUMARATE
نویسندگان
چکیده
منابع مشابه
Preformulation and Formulation Studies of Novel pH Independent Controlled Release Drug Delivery System of Quetiapine Fumarate
Advent of pharmacology, combinatorial chemistry and High Through Put Screening offered large number of synthetic drugs as a therapeutic substances. These molecules are potent to elucidate their pharmacological activity. However, pharmacokinetic properties of such molecules are rate limiting factors for its safety as well as efficacy. Most of the synthetic drug available so far in market are eit...
متن کاملFormulation Development and Evaluation of Orodispersible Tablets of Quetiapine Fumarate by Sublimation Method
The objective of present study was to formulate directly compressible orodispersible tablets of quetiapine fumarate by sublimation method with a view to enhance patient compliance. A full 32 factorial design was used to investigate the effect of two variables viz., concentration of Indion 414 and camphor. Indion 414 (3-5 % w/w) was used as superdisintegrant and camphor (5-15 % w/w) as subliming...
متن کاملFormulation and In-vitro Evaluation of Tretinoin Microemulsion as a Potential Carrier for Dermal Drug Delivery
In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...
متن کاملFormulation and In-vitro Evaluation of Tretinoin Microemulsion as a Potential Carrier for Dermal Drug Delivery
In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...
متن کاملElectrochemical studies for the determination of quetiapine fumarate and olanzapine antipsychotic drugs.
PURPOSE Cyclic voltammetry and differential pulse voltammetry were used to explore the diffusion behavior of two antipsychotic drugs at a glassy carbon electrode. A well-defined oxidation peak was obtained in Britton-Robinson (BR) buffer (pH 2.0). The response was evaluated as a function of some variables such as the scan rate, and pH. METHODS A simple, precise, inexpensive and sensitive volt...
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ژورنال
عنوان ژورنال: International Journal of Research in Ayurveda and Pharmacy
سال: 2013
ISSN: 2277-4343
DOI: 10.7897/2277-4343.04237